Nondisjunction in males can lead to XY, O or XX and YY sperm (MII only) .
Combining these with an X egg will produce the syndromes described
above plus XYY (Jacobs).

Females with the karyotype 47; XXX are fertile, tend to have XX and XY
offspring, generally fall in the normal range of IQ, and have no
distinguishing characteristics. Many are considered "shy" when young
and may be delayed in social development. There is great tendency for
metal retardation when there are 4, 5, or 6-X chromosomes present.
Overall frequency: about 1 in 4,000 live births.

Females with Turners syndrome (45; XO) are very short, sterile, and have
problems with "spatial" tests but otherwise tend to fall in the normal IQ
range. Development of secondary sex characteristics and stature can be
addressed by hormone therapy. Heart and kidney problems are also
common. Frequency: 1 in 2,000 to 1 in 2,500 live female births

Klinefelter males (47; XXY) tend to be tall, are infertile with very small
testes, generally lag in development of language skills, and often display
breast development at puberty. The latter is easily treated with
testosterone, but fertility is not restored. Frequency is estimated at 1 in
500 to 1 in 1,000 male births.

XYY males also tend to be taller than average and have problems with
acne but are fertile and have XY and XX children. As a group they
generally fall near the normal IQ range. Although there is increased
"risk" for XYY males to end up in penal institutions (about 1 in 300 males
in prison is XYY compared to 1 in 1,000 at birth) the vast majority are in
the normal population. Early studies suggesting "super" aggressive male
behavior have not been borne out.

SEX DETERMINATION IN MAN

Based on the previous information, it is clear that the primary
determinant of sex in humans is the presence or absence of the Y
chromosome, which is determined at fertilization; no Ys results in female
development; 1 Y, no matter how many Xs, produces male development.