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The molecular sculpture of (North)-methanocarba-thymidine
shown above has been executed in pear wood.
It is a gift to Prof. Dr. Gerd Folkers, in appreciation
for his help on many occasions, especially for writing a letter to the
US National Science Foundation in support of the proposal to fund research
in molecular modelling and sculpting.
The title compound is bound in the active site of the
enzyme, herpes simplex virus type 1 thymidine kinase.
The crystal structure was determined by A.Prota, J.Vogt,
B.Pilger, R.Perozzo, C.Wurth, V.Marquez, P.Russ, G.E.Schulz, G.Folkers
& L.Scapozza and published in BIOCHEMISTRY 39: 9597 (2000).
E. Meyer fecit, 2001
Other examples in this series include:
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