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Texas A&M University System Health Science Center

Department of Systems Biology and Translational Medicine

G. D. Alpini, H. J. Granger (Head), R. K. Hester, L. Kuo, C. J. Meininger, M. Muthuchamy, J. L. Parker, A. R. Parrish, T. V. Peterson, W. Sampson, E. E. Smith, A. Trache, J. P. Trzeciakowski, V. J. Van Buren, E. Wilson, D. C. Zawieja, W. Zimmer

(SBTM)

601. Methods in Molecular and Cell Biology. (3-3). Credit 4.

Fundamental laboratory techniques used to investigate cellular and subcellular structure and function; cell culture and isolation; light microscopy (brightfield, phase, DIC); fluorescence microscopy; confocal and multiphoton microscopy; atomic force microscopy; protein isolation, concentration and quantification; gel electrophoresis; immunoprecipitation; agarose gel electrophoresis; northern, southern and western blotting; transfections and plasmid preps; polymerase chain reaction; microarray technology. Prerequisites: Graduate classification in SBTM or medical sciences and approval of course coordinator.

602. Theory of Molecular and Cell Biology. (2-0). Credit 2.

Equivalent to lecture component of SBTM 601. No laboratory. Prerequisites: Graduate classification and approval of course coordinator.

603. Cardiovascular Science. (3-0). Credit 3.

Molecular basis of cardiomyocyte, endothelial and vascular smooth muscle functions; structure and function of heart and vasculature; cardiovascular mechanics; local, hormonal and nervous control mechanisms; integrative behavior of cardiovascular system; cardiovascular pathobiology. Prerequisites: MSCI 601 & 602 or equivalent and approval of course coordinator.

604. Advanced Cardiovascular Biology I. (4-0). Credit 4.

Biology of cardiogenesis, vasculogenesis, lymphangiogenesis and hematopoiesis; functions of heart, and blood and lymph vascular systems; integrated molecular and cellular mechanisms that regulate cardiovascular network. Prerequisite: SBTM 603 or VTPP 910 & 912 and MSCI 601 & 602 and approval of course coordinator.

606. Advanced Cardiovascular Biology II. (4-0). Credit 4.

Interactions of the heart and vascular system including intrinsic, neural and humoral control systems; molecular genetics and pathophysiology of cardiovascular system during the development of diseases; gene therapy approaches in cardiovascular biology. Prerequisites: SBTM 604 and approval of course coordinator.

608. Bone Biology. (2-0). Credit 2.

Introduction to the discipline of bone; discussion includes all aspects of bone biology. Prerequisite: Graduate classification in SBTM or medical sciences, or approval of instructor.

681. Seminar. Credit 1.

Focus will be on critical scientific thinking. Emphasis placed on oral communications, scientific writing and grant preparation. Prerequisite: Graduate student in medicine. Approval of instructor.

685. Directed Studies. Credit 1-6 each semester.

Limited investigation in fields other than those chosen for thesis or dissertation. Prerequisite: Approval of instructor.

689. Special Topics In.... Credit 1 to 4.

Selected topics in an identified area of System Biology and Translational Medicine. May be repeated for credit when topics vary. Prerequisite: Approval of the instructor.