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The Texas A&M University System

Health Science Center—College of Medicine

Neurosciences and Experimental Therapeutics

P. C. Brandt, W.-J. A. Chen, G. C. Chiou, D. P. Dohrman, D. J. Earnest, G. D. Frye, J. B. Gelderd, W. H. Griffith (Head), J. Hubbard, G. C. McCord, R. C. G. Miranda, F. Sohrabji, J. R. West, U. H. Winzer-Serhan

(NEXT)

601. Advanced Neurosciences. (1-2). Credit 2.

Details of mammalian nervous system, including humans; focus on organization of functional neural systems and their integrative action; use of original research papers. Prerequisites: MANA 922 and approval of instructor.

603. Neuropsychopharmacology. (4-0). Credit 4.

Pharmacology as it relates to behavior and the central nervous system. Prerequisites: MPHM 923, 924 and 925 or equivalents.

604. Special Regional Human Dissections. Credit 1 to 3 each semester.

Dissection of special region with more detail than in MANA 901; histological, neural and gross anatomical material utilized. Prerequisites: MANA 901 and approval of instructor.

605. Molecular Mechanisms of Drug and Toxin Action I. (4-0) Credit 4.

Introduction to the major tools and concepts of pharmacology. This is a two part series (see MPHM 606). By the end of these courses, the student will understand how selectivity of drug action is determined by pharmacological principles and will have a scientific basis for a rational approach to the study of drug actions and side effects. Prerequisite: approval of coordinator.

606. Molecular Mechanisms of Drug and Toxin Action II. (4-0). Credit 4.

Survey of ocular drugs, overview of molecular signaling mechanisms and selected topics in developmental neuropharmacology. Prerequisite: permission of coordinator.

607. Molecular Mechanisms of Drug and Toxin Action III. (4-0). Credit 4.

Interaction of drugs and toxins with neurotransmitter systems with primary emphasis on mechanisms involving receptor function that impacts central nervous system integration. Prerequisite: approval of coordinator.

608. Methods in Neurohistology. (1-2). Credit 2.

Instruction in anesthetization, perfusion of animals; removal of neural tissues; histological processing, staining of tissues, including immunohistochemistry. Prerequisites: MANA 911 and approval of instructor.

609. Intracellular Signaling. Credit 1-2.

Introduction to signaling pathways inside cells that mediate multi-step cascades following cell surface receptor activation and how these pathways are influenced by drugs. Prerequisite: approval of coordinator.

610. Organ-specific Toxicology. (1-0). Credit 1.

Introduction to critical mechanisms of toxic injury of organ systems with emphasis on liver, kidney, lung, central nervous system and reproductive tract and overview of classic toxicants. Prerequisite: approval of coordinator.

621. Teaching Gross Anatomy. (3-8). Credit 2.

Provides teaching and supervisory experience for graduate students; instructs students in teaching and supervising medical students in gross anatomy (MANA 901); student(s) observe in the laboratory and present at least one lecture. Prerequisites: completion of MANA 901 with a grade of “B” or better and approval of course coordinator.

622. Teaching Medical Histology. (2-4). Credit 1.

Provides teaching and supervisory experience for graduate students; instructs students in teaching and supervising medical students in microscopic anatomy (MANA 911); student(s) observe in the laboratory and present at least one lecture. Prerequisites: taken and passed MANA 911.

623. Teaching in Medical Neuroscience. (5-3). Credit 2.

Assist in the teaching of medical neuroscience (MANA 922), to include lecture(s), laboratories and examination setup and proctoring. Prerequisite: MANA 922, approval of instructor, and taken and passed neurosciences.

681. Seminar. Credit 1.

Focus will be on critical scientific thinking. Emphasis placed on oral communications, scientific writing and grant preparation. Prerequisite: graduate student in medicine. Approval of instructor.

685. Directed Studies. Credit 1-6 each semester.

Limited investigation in fields other than those chosen for thesis or dissertation. Prerequisite: approval of instructor.

689. Special Topics In.... Credit 1 to 4.

Selected topics in an identified area of pharmacology and toxicology. May be repeated for credit when topics vary. Prerequisite: approval of the instructor.