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The Texas A&M University System Health Science Center—College of Medicine

Department of Medical Pharmacology and Toxicology

P. C. Brandt, G. C.-Y. Chiou (Head), G. D. Frye, W. H. Griffith III, R. K. Hester, B. A. McCool, A. R. Parrish, J. P. Trzeciakowski, J. L. Way, U. Winzer-Serhan, W. E. Zimmer

(MPHM)

603. Neuropsychopharmacology. (4-0). Credit 4.

Interaction of drugs and toxins with neurotransmitter systems; emphasis on mechanisms involving receptor function that impact central nervous system. Prerequisites: Approval of coordinator.

604. Quantifying Drug Action. Credit 2.

Introduction to the basic tools for analyzing drug effects data collected in systems ranging from tissues, to cells to subcellular (receptor) preparations. Prerequisite: Approval of coordinator.

605. Molecular Mechanisms of Drug and Toxin Action I. (4-0). Credit 4.

Introduction to the major tools and concepts of pharmacology. This course is the first of a two-part series (see MPHM 606 Molecular Mechanisms of Drug Toxin Action II). Lecture topics include: General concepts of pharmacological agents and substances; pharmacokinetics, pharmacodynamics, autonomic drugs; ocular pharmacology, cardiovascular pharmacology; anesthetics; nueropsycopharmacology; analgesics; chemotherapy, endocrine pharmacology, autacoids; drug abuse and medical toxicology. Prerequisite: Approval of coordinator.

606. Molecular Mechanisms of Drug and Toxin Action II. (4-0). Credit 4.

Introduction to the major tools and concepts of pharmacology. This course is the second of a two-part series (see MPHM 606 Molecular Mechanisms of Drug Toxin Action II). Lecture topics include: General concepts of pharmacological agents and substances; pharmacokinetics, pharmacodynamics, autonomic drugs; ocular pharmacology, cardiovascular pharmacology; anesthetics; nueropsycopharmacology; analgesics; chemotherapy, endocrine pharmacology, autacoids; drug abuse and medical toxicology. Prerequisite: Approval of coordinator.

607. Ocular Pharmacology and Therapeutics III. Credit 1.

Introduction to the anatomy and physiology of the eye, and the etiology and pharmacological treatments of various eye diseases, including glaucoma, uveitis, retinopathy, age-realted macular degeneration, myopia, dry eye syndrome, cataract, and eye cancers. Relevant drug treatments, mechanisms of drug actions, side effects, advantages and disadvantages addressed. Prerequisite: Approval of coordinator.

608. Organ-Specific Toxicology. Credit 1.

Introduction to factors influencing organ-specific responses to toxicants including, mechanisms of toxic injury to the liver, kidney, lung, central nervous system, and reproductive tract, and classic toxicants such as hydrocarbons (benzo(a)pyrene and dioxin), metals (lead, mercury and arsenic) and pesticides. Prerequisite: Approval of coordinator.

609. Intracellular Signaling. Credit 1 to 2.

Introduction to intracellular pathways, multi-step cascades, that are downstream of the site of action of drugs. Also an introduction to potential signaling modifications that may serve as new drug targets. Prerequisite: Approval of coordinator.

923. Medical Pharmacology. (7-3). Credit 7.

General concepts of pharmacological agents and substances: pharmacokinetics, pharmacodynamics, antimicrobial and antineoplastic agents; autonomic drugs; and toxicology. Endocrine pharmacology, renal pharmacology, cardiovascular pharmacology, respiratory pharmacology, neuropharmacology. Prerequisite: Admission to medical curriculum or MEID 905, MANA 922, MBCH 914 or approval of department head.