Course Descriptions
Department of Veterinary Physiology and Pharmacology
H. R. Adams, E. M. Bailey, Jr., N. P. Clarke, T. A. Cudd, C. L. Heaps, J. D. Herman, K. Hinrichs, D. M. Hood, J. F. Hunter, I. Ivanov, D. H. Jones, D. T. Kochevar, D. C. Kraemer, G. A. Laine (Head), C. R. Long, P. E. Mirkes, C. M. Quick, A. J. Roussel, Jr., E. B. Rucker, III, S. H. Safe*, F. Schroeder, J. N. Stallone, R. H. Stewart, Y. Tian, J. S. Wasser*, M. E. Westhusin, C. Zhang
* Graduate Advisor
Graduate programs leading to the Master of Science and Doctor of Philosophy degrees in physiology or toxicology are designed to prepare the graduate for research, teaching and other related areas. Faculty specialty areas include cardiovascular physiology, gamete and embryo physiology, endocrinology, comparative oncology, equine laminitis, cellular and molecular biology, clinical pharmacology, and veterinary, plant and environmental toxicology. Several departmental faculty members serve on the intercollegiate faculties of genetics and toxicology.
There is no departmental requirement for foreign languages. These are considered in the same status as other supplementary areas of study to be included when indicated by the individual needs of students.
Veterinary Physiology and Pharmacology
(VTPP)
605. Systemic Veterinary Physiology I. (5-0). Credit 5.
Aspects of cellular physiology, physiology of excitable membranes, physiology of body fluids, neurophysiology, and the physiology of smooth, cardiac and skeletal muscle; provides a basic understanding of mammalian physiology essential as a framework for advanced graduate studies. Prerequisite: Graduate classification.
606. Systemic Veterinary Physiology II. (5-0). Credit 5.
In-depth study covering cardiovascular, respiratory, renal physiology, gastrointestinal and endocrine physiology; provides a basic understanding of mammalian physiology essential as a framework for advanced graduate studies. Prerequisite: VTPP 605.
653. Endocrinology. (3-3). Credit 4.
Physiology, biochemistry and pharmacology of the endocrines. Laboratory emphasizes a number of classical experiments with clinical application. Prerequisite: Approval of instructor
654. Molecular Endocrinology. (3-0). Credit 3.
Structure-function relationships of hormones, their receptors and biologic activities. Prerequisites: VTPP 653 or ZOOL 649 and BICH 410 or equivalent or approval of instructor. Cross-listed with ANSC 654.
655. Vascular Physiology. (4-0). Credit 4.
Structure and function of blood vessels and vascular beds; molecular and cell biology of endothelium and vascular smooth muscle; microcirculation; capillary exchange; regulation of blood flow by local, neural and humoral signals. Prerequisite: MPHY 901 or approval of department head.
656. Physiology of the Heart. (4-0). Credit 4.
Structure and function of the heart; molecular and cell biology of cardiac myocytes; electrophysiology of myocardium, pacemaker cells and conducting tissue; cardiac mechanics; control of cardiac performance; coronary circulation. Prerequisite: MPHY 901 or 604 or approval of department head.
657. Cardiovascular Physiology. (3-3). Credit 4.
Physiological considerations of the circulatory system including general and integrative aspects of the heart and blood vessels. Prerequisites: Approval of instructor.
658. Anatomy and Physiology of the Equine Foot. (3-0). Credit 3.
In-depth study of the anatomy and physiology of the foot of the horse; includes both gross and histologic anatomy, metabolic and nutrition and biomechanics of the equine foot. Prerequisites: VTPP 323 and 423.
659. Gamete and Embryo Physiology. (2-2). Credit 3.
Physiology of gametes and preimplantation embryos in livestock and laboratory animals; oocyte growth and maturation in-vivo and in-vitro, fertilization in-vivo and in-vitro, embryo transfer, cryopreservation, nuclear transfer, chimera formation, gene transfer.
665. Pharmacology. (3-3). Credit 4.
Pharmacokinetic and pharmacodynamic principles of pharmacology, absorption, biotransformation, distribution, excretion, dose-response relationships, adverse reactions, and interactions. Prerequisites: Undergraduate, professional or equivalent course in physiology, pharmacology, biochemistry, introductory calculus.
667. Current Topics in Pharmacology. (3-0). Credit 3.
Discussions of literature regarding topics of current research interest; physiochemical or physiologic effects of drugs at sites from molecular to whole body. Prerequisite: Approval of instructor.
670. Toxicology. (3-3). Credit 4.
Fundamentals of toxicology including the disease syndromes produced in humans and animals by organic and inorganic chemicals; environmental factors in intoxications. Prerequisites: Advanced standing in biochemistry and physiology; approval of instructor.
671. Toxicity Testing Concepts. (2-2). Credit 4.
Approval processes for compliance with federal drug and chemical laws. Prerequisites: VTPP 665 and 670 or approval of instructor.
672. Toxic Plants and Biotoxins. (2-3). Credit 3.
An examination of the disease syndromes produced in animals and humans by native, ornamental and introduced plants, vertebrate and invertebrate toxins and mycotoxins; field trips for plant identification. Prerequisites: VTPP 670; approval of instructor.
673. Metabolic and Detoxication Mechanisms. (3-0). Credit 3.
Fate of foreign compounds; their inhibitory and antagonistic action toward normal metabolic processes of the animal body. Prerequisites: BICH 603; approval of instructor and department head.
674. Natural Products Toxicology. (3-0). Credit 3.
Occurrence, identification and metabolism of naturally occurring toxicants of plant, animal and microbial origin. Prerequisites: CHEM 628; approval of instructor.
675. Industrial and Environmental Toxicology. (3-0). Credit 3.
Fundamentals of toxicology and risk assessment; effects of selected classes of hazardous chemicals encountered in the workplace or environment on human health will be considered. Prerequisite: Approval of instructor.
676. Genetic and Molecular Toxicology. (3-0). Credit 3.
Mechanisms of toxicant-induced target organ toxicity with emphasis on molecular control of mammalian and cell growth differentiation. Prerequisite: Graduate course in cell biology and biochemistry.
677. Fluorescence Detection: Steady State, Time Resolved and Imaging. (3-0) Credit 3.
Fluorescence techniques used by biological scientists in their research, evaluation of the literature in the field, pursuit of resources, interactions with colleagues and resulting from the extension and technological opportunities available through spectroscopy; introduces graduate students in pharmacology, toxicology, biochemistry, molecular biology, and other life sciences to these issues at an early stage in their careers; develops thinking skills to make informed judgments on applicability of fluorescence techniques, evaluating the literature and in presentations, and communicate their rationales to other scientists. Prerequisite: General chemistry and biology course.
681. Seminar. (1-0). Credit 1.
Review and discussion of current scientific work in physiology and related subjects. Prerequisite: Approval of department head.
685. Directed Studies. Credit 1 to 4 each semester.
Problems in physiology, pharmacology or toxicology. Prerequisite: Approval of instructor.
689. Special Topics in... Credit 1 to 4.
Selected topics in an identified area of veterinary physiology and pharmacology. May be repeated for credit. Prerequisite: Approval of instructor.
690. Theory of Research. (3-0). Credit 3.
Theory and design of research related to current biomedical problems especially those involving study of animal disease; philosophical perspectives underlying historical advances in research pertaining to the study, prevention and treatment of disease. Prerequisite: Graduate classification. Cross-listed with VIBS 690 and VPAT 690.
691. Research. Credit 1 or more each semester.
Original investigations in veterinary physiology, pharmacology or toxicology to be submitted by writing of thesis or dissertation as partial fulfillment for MS or PhD degree. Prerequisite: Approval of department head.