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The Texas A&M University System
Health Science Center--College of Medicine

Department of Medical Biochemistry and Medical Genetics

S. M. Dobin, A. C. R. Ficht, P. D. Gershon, F. S. Gimble, G. M. Ihler, Y. W. Jiang, A. E. Johnson, G. M. Kapler, T. J. Kuehl, G. D. LeSage, M. Liu, J. F. Martin, S. Musser, C.N. Pace, J. M. Scholtz (Interim Head), R. R. Sinden, L. C. Skow, D. K. Struck, J.E. Womack

(MBCH)

601. Medical Molecular Biology. (3-0). Credit 3.

Application of recombinant DNA techniques to the diagnosis and study of human genetic and transmissible diseases; molecular biology as applied to the study of human pathogens and to the function of the human immune system. Prerequisite: MBCH 913 or equivalent or approval of instructor.

604. Developmental and Cellular Biochemistry. (3-0). Credit 3.

Basic structure and function of eukaryotic cells with special emphasis on biochemical communication between internal cell compartments and between cells and their environment; molecular basis of differentiation; oncogenes and disorders of differentiation in humans. Prerequisite: MBCH 911 or approval of instructor.

625. Nucleic Acid--Protein Interactions. (1-0). Credit 1.

Mechanisms of nucleic acid-protein interactions involved in fundamental biochemical processes such as DNA replication and rearrangement, transposition, transcription, RNA splicing and translation; original research articles presented focusing on experimental approaches, interpretation of results and overall significance. Course may be taken 8 times for credit. Prerequisites: BICH 431 or GENE 431 or equivalent; approval of instructor. Cross-listed with BICH 625.

671. Macromolecular Folding and Design. (1-0) Credit 1.

Oral presentations and discussions in the general area of biomolecular structure, folding, function and design. May be taken 12 times. Prerequisite: Approval of instructor. Cross-listed with BICH 671 and CHEM 671.

672. Biological Membranes. (1-0). Credit 1.

Seminar-based course examining recent discoveries in the structure, function and assembly of biological membranes; oral presentation by students on current literature in molecular biology and biochemistry. Prerequisite: Approval of instructor. Cross-listed with BICH 672.

674. Protein Folding and Stability. (1-0). Credit 1.

Selected topics from recent literature in the general areas of protein folding, structure, and stability. Prerequisite: Approval of instructor. Cross-listed with BICH 674.

914. Medical Biochemistry, Genetics and Nutrition. (10-0). Credit 10.

Properties and metabolism of proteins, nutritional biochemistry, nutritional deficiencies, diet and disease. The metabolic basis of inherited disease; metabolism of lipids, carbohydrates, amino acids, purines and pyrimidines. Properties and metabolism of DNA and RNA, fundamentals of medical genetics, including diseases resulting from inborn errors of metabolism, chromosomal abnormalities, human gene mapping and applications of recombinant DNA technology to problems of human genetics. Prerequisite: Admission to the medical curriculum or approval of the department head.