601. Microbial Pathogenesis of Human Disease. (3-0). Credit 3.

Principles of microbe-host interactions described at the molecular level and understood by current research literature; general concepts of various pathogenic mechanisms frame the introductory section; selected medically important infectious diseases serve as paradigms with detailed molecular models of how multiple pathogenic mechanisms contribute to disease. Prerequisite: Approval of instructor.

602. Immunoregulation. (3-0). Credit 3.

In-depth exploration of the genetic, cellular and molecular mechanisms by which humoral and cellular immune responses are regulated; regulatory T cell circuits, molecules (interleukins, lymphokines), isotypic and idiotypic regulation, hormonal effects, immunoregulatory defects, experimental manipulation of immunoregulatory networks. Prerequisites: BIOL 610 or VTMI 649; approval of instructor.

607. Applied Epidemiology. (3-3). Credit 4.

Application of epidemiologic concepts to the study of disease occurrence; descriptive epidemiologic methods in the study of diseases. Prerequisite: Graduate classification.

663. Molecular Biology of Viruses. (3-0). Credit 3.

In-depth studies of the biochemistry and the replication strategies of viruses and molecular mechanisms of pathogenesis for selected viral systems. Prerequisite: Graduate classification in pathology, molecular biology, biochemistry or approval of instructor. Cross-listed with VTMI 663.

923. Medical Microbiology I. (2-4). Credit 4.

General concepts of immunological and microbiological principles and phenomena in relation to clinical manifestations of infectious disease in the human host and mechanisms of the immune response. Prerequisite: Admission to medical curriculum or approval of department head.

924. Medical Microbiology II. (2-4). Credit 4.

Continuation of 923. Prerequisite: MMIM 923.