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Department of Medical Biochemistry
and Medical Genetics
H. Bayley, S. M. Dobin, A. C. R. Ficht, P. D.
Gershon, F. S. Gimble, G. M. Ihler, Y. W. Jiang, A. E. Johnson,
G. M. Kapler, T. J. Kuehl, G. D. LeSage, M. Liu, J. F. Martin,
S. Musser, C.N. Pace, J. M. Scholtz (Interim Head), R. R. Sinden,
L. C. Skow, D. K. Struck, J.E.Womack
(MBCH)
601. Medical Molecular Biology.
(3-0). Credit 3.
Application of recombinant DNA
techniques to the diagnosis and study of human genetic and
transmissible diseases; molecular biology as applied to the
study of human pathogens and to the function of the human immune
system. Prerequisite: MBCH 913 or equivalent or approval of
instructor.
604. Developmental and Cellular
Biochemistry. (3-0). Credit 3.
Basic structure and function of
eukaryotic cells with special emphasis on biochemical communication
between internal cell compartments and between cells and their
environment; molecular basis of differentiation; oncogenes
and disorders of differentiation in humans. Prerequisite: MBCH
911 or approval of instructor.
625. Nucleic Acid--Protein
Interactions. (1-0). Credit 1.
Mechanisms of nucleic acid-protein
interactions involved in fundamental biochemical processes
such as DNA replication and rearrangement, transposition, transcription,
RNA splicing and translation; original research articles presented
focusing on experimental approaches, interpretation of results
and overall significance. Course may be taken 8 times for credit.
Prerequisites: BICH 431 or GENE 431 or equivalent; approval
of instructor. Cross-listed with BICH 625.
671. Macromolecular Folding
and Design. (1-0) Credit 1.
Oral presentations and discussions
in the general area of biomolecular structure, folding, function
and design. May be taken 12 times. Prerequisite: Approval of
instructor. Cross-listed with BICH 671 and CHEM 671.
672. Biological Membranes.
(1-0). Credit 1.
Seminar-based course examining
recent discoveries in the structure, function and assembly
of biological membranes; oral presentation by students on current
literature in molecular biology and biochemistry. Prerequisite:
Approval of instructor. Cross-listed with BICH 672.
911.
Medical Biochemistry and Nutrition: Macromolecules, Molecular
Biology
and Molecular Genetics. Credit 5.
Properties and metabolism
of proteins; introduction to the metabolic basis of inherited
disease. Prerequisite: Admission to the medical curriculum
or approval of department head.
913. Medical Genetics. Credit
5.
Properties and metabolism of DNA
and RNA; fundamentals of medical genetics, including diseases
resulting from inborn errors of metabolism, chromosomal abnormalities,
human gene mapping; applications of recombinant DNA technology
to problems of human genetics. Prerequisite: MBCH 911.
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