601. Foundations of Biomedical Engineering Analyses. (3-0). Credit 3.

Analysis of biomedical engineering processes involving interactions between biological tissues and electromagnetic waves using methodologies from developed physical principles; applications include electric and magnetic fields in biological tissues, and electromagnetic wavetreatment of fundamental light propogation properties in biological tissues such as transmission, reflection, polarization, interference and diffraction. Prerequisite: MATH 308.

602. Instrumentation and Measurement in Biomedical Systems. (3-3). Credit 4.

Information measurement from biomedical systems; interface matching; transducers commonly used in biomedical engineering as the interface between biomedical signals and instrumentation systems. Prerequisites: BMEN 309 and 401 or equivalent.

603. Information Processing in Biomedical Engineering. (3-3). Credit 4.

Methods for evaluating alternative approaches in signal processing systems for biomedical applications; provides familiarity with the wide variety of existing software and hardware systems. Prerequisite: BMEN 309.

605. Virtual Instrumentation Design for Medical Systems. (2-3). Credit 3.

Design of medical systems using graphics programming language of LabVIEW including the designing and programming of three virtual systems: cardiac monitor, electromyogram system for biomechanics, and sleep stage analyses for electroencephalograms. Prerequisite: Graduate classification.

608. Optical Diagnostic and Monitoring Principles. (3-0). Credit 3.

Engineering design principles of optically based monitoring and diagnostic modalities; emphasis on generating quantitative descriptions of biochemical and biophysical interactions of optic and fiber optic systems as applied to medical diagnostics and sensing. Prerequisites: MATH 308; PHYS 208.

609. Optical Therapeutic and Interventional Principles. (3-0). Credit 3.

Study of optical and thermal processes of laser interaction with biological tissue; issues and objectives in therapeutic, surgical and diagnostic applications; basic engineering principles used in developing therapeutic with a focus on the use of lasers and optical technology. Prerequisite: MATH 308; PHYS 208.

611. Biomedical Imaging Systems. (3-0). Credit 3.

The physics behind the major medical imaging systems including CT, MRI, Ultrasound and X-Ray will be introduced and described; a linear systems approach will be used along with basic diffraction theory. Prerequisites: BMEN 309; MATH 308.

612. Experimentation. (2-3). Credit 3.

General concepts forming the basis of the scientific method and design of experiments; analytical instrumentation and measurement methods useful in biomedical research; criteria for the selection, care and use of experimental animals and human subjects in biomedical research. Prerequisite: 3 hours in physiology.

614. Modeling of Biomedical Systems. (3-0). Credit 3.

Principles, objectives and approaches to describing physiological phenomena with mathematical models with emphasis on mammalian systems. Prerequisites: 3 hours in physiology; 3 hours in differential equations.

620. Bio-Optical Imaging. (3-0). Credit 3.

Optical imaging techniques for detection of structures and functions of biological tissues; basic physics and engineering of each imaging technique. Prerequisites: BMEN 601; MATH 308.

630. Global Medical Device Regulation. (3-0). Credit 3.

Overview of applicable U.S. and international regulations and regulatory processes for the design, approval and marketing of medical devices. Prerequisites: BMEN 310 and graduate classification.

635. Biomaterials Compatibility. (3-0). Credit 3.

Relevance of mechanical and physical properties to implant selection and design; effect of the body environment on metallic, ceramic and plastic materials; tissue engineering; rejection mechanisms used by the body to maintain homeostasis regulatory requirements. Prerequisite: Approval of instructor.

638. Control Mechanisms in Living Systems. (3-0). Credit 3.

Application of control theory to the dynamic characteristics of electro-physiological and biochemical processes and to the natural and artificial maintenance of homeostasis in living systems. Prerequisites: BMEN 401; MATH308; 3 hours of physiology.

640. Design of Medical Devices. (3-0). Credit 3.

Overview of the multiple issues in managing the design of a marketable medical device, including the design process from clinical problem definition through prototype and clinical testing to market readiness; includes FDA pre- and post-market regulation, human factors and system safety considerations, and medical product liability. Prerequisite: Graduate classification in engineering.

650. Biomedical Optics Laboratory. (2-3). Credit 3.

Biomedical optics technology; basic engineering principles used in developing therapeutic and diagnostic devices; a series of hands-on labs will be performed including optical monitoring, diagnostic and therapeutic experiments. Prerequisites: MATH 308; PHYS 208.

660. Vascular Mechanics. (3-0). Credit 3.

Application of continuum mechanics to the study of the heart arteries; on the measurement and quantification of material properties, and the calculation of vascular stresses; analysis of several cardiovascular devices to reinforce the need for careful analysis in the device design. Prerequisites: BMEN 302 and 421 or equivalents; graduate classification.

661. Cardiac Mechanics. (3-0). Credit 3.

Application of continuum mechanics and computational solid mechanics to the study of the mammalian heart; utilization of continuum mechanics and finite element analysis in solving non-linear boundary value problems in biomechanics. Prerequisites: BMEN 302 and 602; MEMA 467; or equivalents.

668. Biothermomechanics. (3-0). Credit 3.

Application of continuum thermomechanics to quantify soft tissue behavior in response to combined thermal and mechanical loads including thermoelasticity and thermal damage. Prerequisites: BMEN 240, 341, and graduate classification.

673. Radiation Biology. (3-0). Credit 3.

The response of biological systems to ionizing radiation at the molecular, cellular, and organismal levels; effects of different dose levels with emphasis on the underlying mechanisms relevant to long term health effects at low doses. Prerequisite: NUEN 409 or graduate classification. Cross-listed with NUEN 673.

681. Seminar. (1-0). Credit 1.

Designed to permit student to broaden capability, performance and perspective in biomedical engineering via his or her own formal presentation and by presentations from other professionals.

684. Professional Internship. Credit 1 or more each semester.

Training under the supervision of practicing engineers in settings appropriate to the student's professional objectives. Prerequisites: Approval of chair of student's advisory committee and department head.

685. Directed Studies. Credit 1 to 12 each semester.

Allows students the opportunity to undertake and complete, for credit, limited investigations not included within thesis or dissertation research and not covered by other courses. Prerequisite: Approval of department head.

689. Special Topics in... Credit 1 to 4.

Selected topics in an identified area of biomedical engineering. May be repeated for credit. Prerequisite: Approval of instructor.

691. Research. Credit 1 or more each semester.

Research for thesis or dissertation.