101. Introduction to Biomedical Engineering. (1-0). Credit 1.

Overview of biomedical engineering and the biomedical engineering industry, including specialties degree requirements and scholastic programs in the Department of Biomedical Engineering. Prerequisite: Freshman or sophomore classification.

240. Biosolid Mechanics. (3-0). Credit 3.

Introduction into the mechanics of deformable media important in biomechanics, including biomaterials and biological tissues with an emphasis on mechanobiology and the formation of biological problems within the context of 1) kinematics including displacements, rotation, strains, 2) the concept of stress, 3) equilibrium, 4) constitutive relations, and 5) boundary conditions. Prerequisite: ENGR 211.

285. Directed Studies. Credit 1 to 4.

Permits students to undertake special projects in biomedical engineering at an earlier point in their studies than required for BMEN 485. Prerequisite: Approval of program chair.

289. Special Topics in... Credit 1 to 4.

Selected topics in an identified area of biomedical engineering. May be repeated for credit. Prerequisite: Approval of instructor.

302. Biomechanics. (3-0). Credit 3. II

Stress and strain in biological systems and medical devices; properties of biomedical engineering materials and design of related equipment. Prerequisites: ENGR 211; VTPP 334; Corequisites: MATH 308; VTPP 335.

305. Bioinstrumentation. (0-3). Credit 1.

Introduction to biomedical instrumentation design; hands on acquisition of biomedical signals; design, building and testing of bioinstrumentation circuits including analog signal amplifiers and analog filter circuits. Prerequisites: ELEN 214, VTPP 334 and 335; junior or senior classification.

308. Biomedical Electronics. (2-3). Credit 4. I

Introduction to basic circuit analysis; characteristics of linear and non-linear circuit elements, design of basic electronic circuits and principles in biomedical engineering and practice of bioelectronic measurements. Prerequisites: ELEN 214; VTPP 334 and 335.

309. Signal Processors for Biomedical Measurements. (3-3). Credit 4. II

Design and application of analog and digital signal processors in biomedical engineering; characteristics of operational amplifiers and selected special purpose integrated circuits; design considerations for analog-to-digital and digital-to-analog circuitry. Prerequisites: BMEN 308; VTPP 334 and 335.

310. Clinical Engineering. (3-0). Credit 3. II

Equipment control concepts and techniques and their application in hospitals and in the medical profession; device evaluation specifications; preventative maintenance and service; calibration, regulation and medical product liability. Prerequisite: BMEN 308.

321. Biomedical Electronics. (3-0). Credit 3.

Introduction to biomedical signals; basic circuit analysis for biomedical signals; design of bioamplifier circuits; characteristics of linear and nonlinear circuit elements; design of basic electronic circuits, principles and practice of bioelectronic measurements. Prerequisites: ELEN 214, VTPP 334 and 335; junior or senior classification.

322. Biosignal Analysis. (3-0). Credit 3.

Design and application of analog and digital signal analysis in biomedical engineering; characteristics of biomedical signals; design considerations for analog-to-digital and digital-to-analog circuitry; biosignal transformation methods; analog and digital filter design for biomedical signals. Prerequisites: BMEN 321, VTPP 334 and 335; junior or senior classification.

331. Theoretical Analysis. (3-0). Credit 3. I

Equations and numerical analysis techniques important to the description of living systems and medical devices; solution alternatives and limitations. Prerequisite: MATH 308.

341. Biofluid Mechanics. (3-0). Credit 3.

Introduction into the mechanics of fluids in biomechanics, including blood, synovial fluid and physiological solutions, with an emphasis on the importance of mechanobiology and the formation of biological problems within the context of 1) kinematics, 2) the concept of stress, 3) linear momentum balance, 4) constitutive relations, and 5) boundary conditions. Prerequisites: BMEN 240; junior or senior classification.

342. Biomaterials and Medical Devices. (3-0). Credit 3.

Selection and use of materials in implantable and tissue contacting medical devices; mass transport in medical devices; regulation and testing of medical devices. Prerequisites: VTPP 335 and BMEN 341; junior or senior classification.

401. Principles and Analysis of Biological Control Systems. (3-0). Credit 3. I

Techniques for generating quantitative mathematical models of physiological control systems and devices; the behavior of physiological control systems using both time and frequency domain methods. Prerequisites: BMEN 308; MATH 308; VTPP 334 and 335.

405. Virtual Instrumentation Design for Medical Systems. (2-3). Credit 3.

Design of medical systems using graphics programming language of LabVIEW including the designing and programming of three virtual systems as follows: cardiac monitor, electromyogram system for biomechanics, and sleep stage analyses from electroencephalograms. Prerequisites: BMEN 308 and 309.

410. Advanced Clinical Engineering. (2-3). Credit 3. I

Training in clinical engineering through hospital-based experience in medical systems technical knowledge, clinical engineering management, technology assessment, and hospital management. Prerequisite: BMEN 310.

420. Medical Imaging. (3-0). Credit 3.

The principles of the major imaging modalities including x-ray radiography, x-ray computed tomography (CT), ultrasonography and magnetic resonance imaging; including a brief discussion on other emerging imaging technologies such as nuclear imaging (PET and SPECT). Prerequisites: MATH 251; junior or senior classification.

421. Biofluid Dynamics. (3-0). Credit 3. I

Biofluid dynamics; derivation of mass and momentum equations; analysis of fluid motion in biomedical engineering systems; dimensional analysis; application of turbulence and boundary layer analysis in biomedical engineering. Prerequisites: BMEN 302; MATH 308; VTPP 334 and 335.

422. Biomaterials and Artificial Internal Organs. (3-0). Credit 3. I

Current practice of material selection and design of artificial internal organs including orthopedic, cardiovascular and other implant applications. Regulations, standards and testing. Prerequisites: BMEN 302; VTPP 334 and 335.

430. Medical Device Regulation. (3-0). Credit 3.

Introduction to the regulations of the U.S. Food and Drug Administration pertaining to testing and marketing medical devices. Prerequisites: BMEN 310; junior or senior classification.

440. Design of Medical Devices. (3-0). Credit 3.

Overview of the multiple issues in designing a marketable medical device, including the design process from clinical problem definition through prototype and clinical testing to market readiness; includes FDA regulation, human factors and system safety considerations and medical product liability. Prerequisites: BMEN 422; senior classification in engineering.

441. Analysis and Design Project I. (0-9). Credit 3. I, II, S

Individual or group biomedical engineering analysis and design project involving problem statement, alternative approaches for solution, specific system analysis and design. Prerequisites: BMEN 309, 421, 452.

442. Analysis and Design Project II. (0-9). Credit 3. I, II, S

Continuation of BMEN 441. Prerequisites: BMEN 309, 421, 452.

450. Case Studies. (1-0). Credit 1.

Examines process through which clinically defined problems are addressed from the perspective of biomedical engineering through the use of case studies; includes issues of technology transfer and clinical evaluation. Prerequisites: BMEN 240, 305 and 342; junior or senior classification.

452. Mass and Energy Transfer in Biosystems. (3-0). Credit 3. II

Transport phenomena associated with physiological systems and their interaction with medical devices; exchange processes in artificial life support systems and diagnostic equipment. Prerequisites: BMEN 421; MATH 308; VTPP 334 and 335.

453. Analysis and Design Project I. (2-0). Credit 2.

Group or team biomedical engineering analysis and design project involving statement, alternative approaches for solution, specific system analysis and design. Prerequisites: BMEN 321, 322 and 342; junior or senior classification.

454. Analysis and Design Project II. (2-0). Credit 2.

Continuation of BMEN 453. Prerequisites: BMEN 321, 322, 342 and 453; junior or senior classification.

460. Vascular Mechanics. (3-0). Credit 3.

Application of continuum mechanics to the study of the heart arteries; emphasis on the measurement and quantification of material properties, and the calculation of vascular stresses; analysis of several cardiovascular devices to reinforce the need for careful analysis in the device design. Prerequisites: BMEN 302 and 421.

461. Cardiac Mechanics. (3-0). Credit 3.

Application of continuum mechanics and computational solid mechanics to the study of the mammalian heart; utilization of continuum mechanics and finite element analysis in solving non-linear boundary value problems in biomechanics. Prerequisites: BMEN 302 and 421; approval of instructor.

462. Vascular Fluid Mechanics. (3-0). Credit 3.

Bio-fluid mechanics of the human circulatory system including examination of disease development and medical treatments. Prerequisites: BMEN 240 or equivalent; junior or senior classification.

463. Soft Tissue Mechanics and Finite Element Methods. (3-0). Credit 3.

Application of continuum mechanics and finite element methods to the study of the mechanical behavior of soft tissues and associative applications in biomedicine. Prerequisites: BMEN 240 or equivalent; junior or senior classification.

468. Biothermomechanics. (3-0). Credit 3.

Introduction to a continuum thermomechanics approach to quantifying soft tissue behavior in response to combined thermal and mechanical loads including thermoelasticity and thermal damage. Prerequisites: BMEN 240 and 341; junior or senior classification.

470. Introduction of Biomedical Optics. (3-0). Credit 3.

Fundamentals of biomedical optics; basic engineering principles used in optical therapeutics, optical diagnostics and optical biosensing. Prerequisites: MATH 308; PHYS 208. Cross-listed with CHEN 470.

485. Directed Studies. Credit 1 to 6. I, II, S

Permits students to undertake special projects in biomedical engineering. Prerequisite: Approval of program chair.

489. Special Topics in... Credit 1 to 4. I, II, S

New or unique areas of biomedical engineering which are of interest to biomedical engineering and other undergraduate students.